On This Episode:
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) represents one of the most complex and physiologically demanding procedures encountered in modern perioperative medicine.
In this episode of Anesthesia Alchemy: Lynn & Garry Unplugged, Garry takes listeners on a deep dive into the anesthetic management of these challenging cases. Rather than a checklist approach, this conversation walks through how to think during a HIPEC case—understanding the phases, recognizing evolving physiology, and staying ahead of rapid changes.
From understanding the surgical phases to anticipating rapid physiologic shifts, this episode is designed to help clinicians build a structured, thoughtful approach to HIPEC anesthesia.
Here’s some of what you’ll hear in this episode:
🔥 HIPEC creates controlled physiologic stress
🧠 Anticipation matters more than reaction
💧 Precision fluid management is critical
🌡️ Temperature swings must be managed actively
🔄 Physiology is constantly evolving
“The goal is not to react quickly… it’s to never need to react quickly.”
- Lynn & Garry
