On This Episode:
An amniotic fluid embolism (AFE) remains one of the most devastating conditions in obstetric practice. In today’s episode, Sass and Jeremy review the pathophysiology, signs and symptoms, and management of this rare, but lethal condition. Included in the management of an AFE is the administration of a trio of medications known as A-OK (Atropine, Ondansetron, and Ketorolac). If you want to brush up on current management techniques for an AFE, hit play…because it’s go time!
Here are some of the things we’ll discuss in this episode:
- An example of this happening recently where Jeremy works.
- How the body reacts when an amniotic fluid embolism occurs.
- Who is most at risk for developing AFE?
- Signs and symptoms to pay attention to.
- The treatment and management of a patient suffering from AFE.
- What is the AOK treatment?
Gara M, Draouil A, Saad AB, et al. Disseminated intravascular coagulation type of amniotic fluid embolism: a challenging case report with favorable outcome. Pan Afr Med J. 2021 Apr 1;38:325. doi: 10.11604/pamj.2021.38.325.23434.
Long M, et al. Atropine, Ondansetron, and Ketorolac: Supplemental Management of Amniotic Fluid Embolism. Oshsner J. 2022 Fall;22(3):253-257. doi: 10.31486/toj.21.0107.
Rath WH, Hoferr S, Sinicina I. Amniotic fluid embolism: an interdisciplinary challenge: epidemiology, diagnosis and treatment. Dtsch Arztebl Int. 2014 Feb 21;111(8):126-32. doi: 10.3238/arztebl.2014.0126.
Rezai S, et al. Atypical Amniotic Fluid Embolism Managed with a Novel Therapeutic Regimen. Obstet Gynecol Clin North Am. 2022 Sep;49(3):439-460. doi: 10.1016/j.ogc.2022.02.015.
Rezai S. et al. Atypical amniotic fluid embolism managed with a novel therapeutic regimen. Case Reports in Obstetrics and Gynecology. 2017, Article ID 8458375.
Shamshiraz AA, et al. Amniotic Fluid Embolism. Obstet Gynecol Clin North Am. 2016 Dec;43(4):779-790. doi: 10.1016/j.ogc.2016.07.001.
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You can see without treatment, moms are going to have some pretty serious outcomes here.